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  • 1.  Phosphorylated Lipid-Conjugated Oligonucleotide Selectively Anchors on Cell Membranes with High Alkaline Phosphatase Expression

    Jin C , He JX , Zou JM , Xuan WJ, Fu T , Wang RW, Tan WH

    Nature Communications, ,[2019]>> Fulltext Link

    Phosphorylated Lipid-Conjugated Oligonucleotide Selectively Anchors on Cell Membranes with High Alkaline Phosphatase Expression
  • 2.  Regulation of Protein Activity and Cellular Functions Mediated by Molecularly Evolved Nucleic Acids

    Tan J, Zhao MM, Wang J, Li AH, Liang L, Zhang LQ, Yuan Q, and Tan WH

    Angewandte Chemie International Edition, 1621-1625 DOI:10.1002/anie.201809010,[2019]>> Fulltext Link

    Regulation of Protein Activity and Cellular Functions Mediated by Molecularly Evolved Nucleic Acids
  • 3.  Generalized Preparation of Two-Dimensional Quasi-nanosheets via Self-assembly of Nanoparticles

    Ca R, Yang T, Lin KT, Lyu YF, Zhu BW, Zhen He Z, Zhang LL, Kitamura Y, Qiu LP, Chen XG, Zhao YL, Chen Z and Tan WH

    Journal of the American Chemical Society, 1725?1734 DOI:10.1021/jacs.8b12415,[2019]>> Fulltext Link

    Generalized Preparation of Two-Dimensional Quasi-nanosheets via Self-assembly of Nanoparticles
  • 4.  Engineering of Bioinspired, Size-controllable and Self-degradable Cancertargeting DNA Nanoflowers via Incorporation of an Artificial Sandwich Base

    Zhang LL, Abdullah R, Hu XX, Bai HR, Fan HH, He L, Liang H, Zou JM, Liu YL, Sun Y, Zhang XB, and Tan WH

    Journal of the American Chemical Society, DOI: 10.1021/jacs.8b10795,[2019]>> Fulltext Link

    Engineering of Bioinspired, Size-controllable and Self-degradable Cancertargeting DNA Nanoflowers via Incorporation of an Artificial Sandwich Base
  • 5.  Spherical directed Synthesis and enhanced cellular internalization of metal-crosslinked DNA micelles

    Lyn YF, Guo Y, Cai R, Peng RZ, Hong CY, Chen XG, Hou WJ, Li XW, Tan J, Zou YX, Zhang XB, Liu QL, and Tan WH

    Angewandte Chemie International Edition, 10.1016/j.chempr.2019.02004,[2019]>> Fulltext Link

    Spherical directed Synthesis and enhanced cellular internalization of metal-crosslinked DNA micelles
  • 6.  Artificial Sandwich Base for Monitoring Single-Nucleobase Changes and Charge-Transfer Rates in DNA

    Abdullah R,Xie ST, Wang RW, ,Jin C, Du YL, Fu T, L Ji, Tan J, Zhang LL, and Tan WH

    Analytical Chemistry, 2074- 2078 DOI:10.1021/acs.analchem.8b04513,[2019]>> Fulltext Link

    Artificial Sandwich Base for Monitoring Single-Nucleobase Changes and Charge-Transfer Rates in DNA
  • 7.  The influence of physiological environment on the targeting effect of aptamer-guided gold nanoparticles

    Ding D, Zhang YL ,Sykes EA , Chen L, Chen Z, and Tan WH

    Nano Research, 129-135 doi: 10.1007/s12274-018-2191-9,[2019]>> Fulltext Link

    The influence of physiological environment on the targeting effect of aptamer-guided gold nanoparticles
  • 8.  A cell membrane-anchoredfluorescent probe for monitoring carbon monoxide release from living cells

    Xu S, Liu HW, Yin X, Yuan L, Huan SF and Zhang XB

    Chemical Science, DOI: 10.1039/c8sc03584a,[2019]>> Fulltext Link

    A cell membrane-anchoredfluorescent probe for monitoring carbon monoxide release from living cells
  • 9.  Engineering of a bioluminescent probe for imaging nitroxyl in live cells and mice

    Li BJ, Wang QQ, Liu HW, Yin X, Hu XX, Yuan L and Zhang XB

    Chemical Science, 1758--1761 DOI: 10.1039/c9cc00211a,[2019]>> Fulltext Link

    Engineering of a bioluminescent probe for imaging nitroxyl in live cells and mice
  • 10.  Hybridization chain reaction-based nanoprobe for cancer cell recognition and amplified photodynamic therapy

    Xiong MY, Rong Q, Kong G, Yang C, Zhao Y, Qu FL, Zhang XB and Tan WH

    Chemical Science, 3065-3068 DOI: 10.1039/c8cc10074h,[2019]>> Fulltext Link

    Hybridization chain reaction-based nanoprobe for cancer cell recognition and amplified photodynamic therapy
  • 11.  Deubiquitylation and stabilization of p21 by USP11 is critical for cell-cycle progression and DNA damage responses

    Deng, TG; Yan, GB; Song, X; Xie, L; Zhou, Y; Li, JL; Hu, XX; Li, Z; Hu, J; Zhang, YB; Zhang, H; Sun, Y; Feng, PF; Wei, D; Hu, B; Liu, J ; Tan, WH; Ye, M

    Proceedings of the National Academy of Sciences, 4678-4683. DOI: 10.1073/pnas.1714938115,[2018]>> Fulltext Link

    Deubiquitylation and stabilization of p21 by USP11 is critical for cell-cycle progression and DNA damage responses
  • 12.  Liquid-state quantitative SERS analyzer on self-ordered metal liquid-like plasmonic arrays

    Tian,L;Su,MK;Yu,FF;Xu,Y; Li,XY;Li,L; Liu,HL;Tan,WH

    Nature Communications, 1-12. DOI: 10.1038/s41467-018-05920-z ,[2018]>> Fulltext Link

    Liquid-state quantitative SERS analyzer on self-ordered metal liquid-like plasmonic arrays
  • 13.   Identification and characterization of DNA aptamers specific for phosphorylation epitopes of Tau protein

    Teng,I-T; Li,XW; Yadikar,H;Yang,ZH;Li,L;Lyu,YF;Pan,XS;Wang,K;Tan,WH

    Journal of the American Chemical Society, 14314–14323. DOI: 10.1021/jacs.8b08645.,[2018]>> Fulltext Link

     Identification and characterization of DNA aptamers specific for phosphorylation epitopes of Tau protein
  • 14.  Supramolecularly engineered circular bivalent aptamer for enhanced functional protein delivery

    Jiang, Y; Pan, XS; Chang, J; Niu, WJ; Hou, WJ; Kuai, HL; Zhao, ZL; Liu, J; Wang, M; Tan, WH

    Journal of the American Chemical Society, 6780-6784. DOI:10.1021/jacs.8b03442,[2018]>> Fulltext Link

    Supramolecularly engineered circular bivalent aptamer for enhanced functional protein delivery
  • 15.  Constructing smart protocells with built-in DNA computational core to eliminate exogenous challenge

    Lyu, YF; Wu, CCh; Heinke, Charles; Han, D; Cai, R; Teng, I-T; Liu, Y; Liu, H Zhang, XB; Liu, QL; Tan, WH

    Journal of the American Chemical Society, 6912-6920. DOI:10.1021/jacs.8b01960,[2018]>> Fulltext Link

    Constructing smart protocells with built-in DNA computational core to eliminate exogenous challenge
  • 16.  Enhanced targeted gene transduction: AAV2 vectors conjugated to multiple aptamers via reducible disulfide linkages

    Wu, Y; Zhang, LQ; Cui, C; Cansiz, S; Liang, H; Wu, CC; Teng, IT; Chen, WJ; Liu, Y; Hou, WJ; Zhang, XB; Tan, WH

    Journal of the American Chemical Society, 2-5. DOI: 10.1021/jacs.7b08518,[2018]>> Fulltext Link

    Enhanced targeted gene transduction: AAV2 vectors conjugated to multiple aptamers via reducible disulfide linkages
  • 17.  A mRNA-initiated, three-dimensional DNA amplifier able to function inside living cells

    He, L; Lu, DQ; Liang, H; Xie, ST; Zhang, XB; Liu, OL; Yuan, Q; Tan, WH

    Journal of the American Chemical Society, 258-263. DOI: 10.1021/jacs.7b09780,[2018]>> Fulltext Link

    A mRNA-initiated, three-dimensional DNA amplifier able to function inside living cells
  • 18.  Nongenetic Approach for Imaging Protein Dimerization by Aptamer Recognition and Proximity-Induced DNA Assembly

    Liang, H; Chen, S; Li, PP; Wang, LP; Li, JY; Li, J; Yang, HH; Tan, WH

    Journal of the American Chemical Society, 4186-4190. DOI: 10.1021/jacs.7b11311,[2018]>> Fulltext Link

    Nongenetic Approach for Imaging Protein Dimerization by Aptamer Recognition and Proximity-Induced DNA Assembly
  • 19.  Engineering a 3D DNA-logic gate nanomachine for bispecific recognition and computing on target cell surface

    Peng,RZ; Zheng XF; Lyu,YF; Xu,LJ; Zhang,XB; Ke,GL; Liu,QL; You,CJ;Shuangyan Huan*, Weihong Tan*

    Journal of the American Chemical Society, 9793–9796. DOI: 10.1021/jacs.8b04319,[2018]>> Fulltext Link

    Engineering a 3D DNA-logic gate nanomachine for bispecific recognition and computing on target cell surface
  • 20.  Simultaneous application of photothermal therapy and anti-inflammatory prodrug using pyrene-aspirin loaded gold nanorod-graphitic-nanocapsules

    Dong, Q; Wang, XW; Hu, XX; Xiao, LQ; Zhang, L; Song, LJ; Xu, ML; Zou, YX; Chen, L; Chen, Z; Tan, WH

    Angewandte Chemie International Edition, 177-181. DOI: 10.1002/anie.201709648,[2018]>> Fulltext Link

    Simultaneous application of photothermal therapy and anti-inflammatory prodrug using pyrene-aspirin loaded gold nanorod-graphitic-nanocapsules
  • 21.  Cross-Linked Aptamer–Lipid Micelles for Excellent Stability and Specificity in Target-Cell Recognition

    Li,XW;Wang,RW;Jiang,Y;Lyu,YF;Sun,H; Liu,Y;Wang,YY;Teng,I-T;Hou,WJ; Cai,R;Cui,C;Li,L;Pan,XS; Sumerlin,BS;Tan,WH

    Angewandte Chemie International Edition, 11589-11593. DOI:org/10.1002/ange.201804156,[2018]>> Fulltext Link

    Cross-Linked Aptamer–Lipid Micelles for Excellent Stability and Specificity in Target-Cell Recognition
  • 22.  Floxuridine Homomeric Oligonucleotides “Hitchhike” with Albumin In Situ for Cancer Chemotherapy

    Jin,C, Zhang,H; Zou,JM; Liu,Y; Zhang,L; Li,FJ; Wang,RW;Xuan,WJ; Ye,M;Tan,WH

    Angewandte Chemie International Edition, 9132-9135. DOI: 10.1002/anie.201804156,[2018]>> Fulltext Link

    Floxuridine Homomeric Oligonucleotides “Hitchhike” with Albumin In Situ for Cancer Chemotherapy
  • 23.  Fluorinated DNA micelles: synthesis and properties

    Zou, JM; Jin, Ch; Wang, RW; Kuai, HL; Zhang, LL; Zhang, XB; Li, J; Qiu, LP; Tan, WH

    Analytical Chemistry, 6843-6850. DOI:10.1021/acs.analchem.8b01005,[2018]>> Fulltext Link

    Fluorinated DNA micelles: synthesis and properties
  • 24.  Versatile in situ synthesis of MnO2 nanolayers on upconversion nanoparticles and their application in activatable fluorescence and MRI imaging

    Wu, Y; Li, D; Zhou, F; Liang, H; Liu, Y; Hou, W.; Yuan, Q; Zhang, XB; Tan, WH

    Chemical Science, DOI: 10.1039/C8SC00490K,[2018]>> Fulltext Link

    Versatile in situ synthesis of MnO2 nanolayers on upconversion nanoparticles and their application in activatable fluorescence and MRI imaging
  • 25.  Aligner-mediated cleavage of nucleic acids and its application to isothermal exponential amplification

    Wu, WH; Zhang, T; Han, D; Fan, HL; Zhu, GZ; Ding, X; Wu, CC; You, MX; Qiu, LP; Li, J; Zhang, LQ; Lian, X; Hu, R; Mu, Y; Zhou, JG; Tan, WH

    Chemical Science, 3050-3055. DOI: 10.1039/c7sc05141g,[2018]>> Fulltext Link

    Aligner-mediated cleavage of nucleic acids and its application to isothermal exponential amplification
  • 26.  Isotopic graphene-isolated-Au-nanocrystals with cellular Raman-silent signals for cancer cell pattern recognition

    Zou, YX; Huang, SQ; Liao, YX; Zhu, XP; Chen, YQ; Chen, L; Liu, F; Hu, XX; Tu, HJ; Zhang, L; Liu, ZK; Chen, Z; Tan, WH

    Chemical Science, 2842-2849. DOI: 10.1039/c7sc05442d,[2018]>> Fulltext Link

    Isotopic graphene-isolated-Au-nanocrystals with cellular Raman-silent signals for cancer cell pattern recognition
  • 27.  An MTH1-targeted nanosystem for enhanced PDT via improving cellular sensitivity to reactive oxygen species

    Fan, HH; Zhang, LL; Hu, XX; Zhao, ZL; Bai, HR; Fu, XY; Yan, GB; Liang, LH; Zhang, XB; Tan, WH

    Chemical Communications, 4310-4313. DOI: 10.1039/c8cc01264d,[2018]>> Fulltext Link

    An MTH1-targeted nanosystem for enhanced PDT via improving cellular sensitivity to reactive oxygen species
  • 28.  DNA-based dynamic reaction network

    Fu, T; Lyu, YF; Liu, H; Peng, RZ; Zhang, XB; Ye, M; Tan, WH

    Analyst, accepted,[2018]>> Fulltext Link

  • 29.  Construction of a fluorine substituted chromenylium-cyanine near-infrared fluorophore for ratiometric sensing

    Zhu, XY; Yuan, L; Hu, XX; Zhang, LL; Liang, YX; He, SY; Zhang, XB; Tan, WH

    Sensors and Actuators B-Chemical, 219-225. DOI: 10.1016/j.snb.2017.12.008,[2018]>> Fulltext Link

    Construction of a fluorine substituted chromenylium-cyanine near-infrared fluorophore for ratiometric sensing
  • 30.  Aptamer-conjugated nanomaterials for specific cancer diagnosis and targeted therapy

    Bai, HR; Fan, HH; Zhang, XB; Chen, Z; Tan, WH

    Acta Physico-Chimica Sinca, 348-360. DOI: 10.3866/PKU.WHXB201708311,[2018]>> Fulltext Link

  • 31.  In situ targeted MRI detection of Helicobacter pylori with stable magnetic graphitic nanocapsules

    Li, YJ; Hu, XX; Ding, D; Zou, YX; Xu, YT; Wang, XW; Zhang, Y; Chen, L; Chen, Z; Tan, WH.

    Nature Communications, 15653. 10.1038/ncomms15653,[2017]>> Fulltext Link

    In situ targeted MRI detection of Helicobacter pylori with stable magnetic graphitic nanocapsules
  • 32.  DNA probes for monitoring dynamic and transient molecular encounters on live cell membranes

    You, MX; Lyu, YF; Han, D; Qiu, LP; Liu, QL; Chen, T; Wu, Cch,S.;Peng, L; Zhang, LQ; Bao, G; Tan, WH.

    Nature Nanotechnology, 453-459. DOI: 10.1038/nnano.2017.23,[2017]>> Fulltext Link

    DNA probes for monitoring dynamic and transient molecular encounters on live cell membranes
  • 33.  Artificial Base zT as Functional “Element” for Constructing Photoresponsive DNA Nanomolecules

    Wang, RW; Jin, C; Zhu, XY; Zhou, LY; Xuan, WJ; Liu, Y; Liu, QL; Tan, WH.

    Journal of the American Chemical Society, 9104–9107. 10.1021/jacs.7b02865,[2017]>> Fulltext Link

    Artificial Base zT as Functional “Element” for Constructing Photoresponsive DNA Nanomolecules
  • 34.  Circular Bivalent Aptamers Enable in Vivo Stability and Recognition

    Kuai, HL; Zhao, ZL; Mo, LT; Liu, H; Hu, XX; Fu, T; Zhang, XB; Tan, WH.

    Journal of the American Chemical Society, 9128–9131. 10.1021/jacs.7b04547,[2017]>> Fulltext Link

    Circular Bivalent Aptamers Enable in Vivo Stability and Recognition
  • 35.  Molecular Elucidation of Disease Biomarkers at the Interface of Chemistry and Biology

    Zhang, LQ; Wan, Sh; Jiang, Y; Wang, YY; Fu, T; Liu, QL; Cao, ZJ; Qiu, LP; Tan, WH.

    Journal of the American Chemical Society, 2532-2540. DOI: 10.1021/jacs.6b10646,[2017]>> Fulltext Link

    Molecular Elucidation of Disease Biomarkers at the Interface of Chemistry and Biology
  • 36.  Fluorescence Resonance Energy Transfer-Based DNA Tetrahedron Nanotweezer for Highly Reliable Detection of Tumor-Related mRNA in Living Cells

    He, L; Lu, DQ; Liang, H; Xie, ST; Luo, C; Hu, MM; Xu, LJ; Zhang, XB; Tan, WH.

    ACS Nano, 4060-4066. DOI: 10.1021/acsnano.7b00725,[2017]>> Fulltext Link

    Fluorescence Resonance Energy Transfer-Based DNA Tetrahedron Nanotweezer for Highly Reliable Detection of Tumor-Related mRNA in Living Cells
  • 37.  Aptasensor with Expanded Nucleotide Using DNA Nanotetrahedra for Electrochemical Detection of Cancerous Exosomes

    Wang, S; Zhang, LQ; Wan, Sh; S, Cansiz; Cui,Ch; Liu, Y; Cai, R; Hong, ChY; Teng, IT; Shi, ML; Wu, Y; Dong, YY; Tan, WH.

    ACS Nano, 3943-3949. DOI: 10.1021/acsnano.7b00373,[2017]>> Fulltext Link

    Aptasensor with Expanded Nucleotide Using DNA Nanotetrahedra for Electrochemical Detection of Cancerous Exosomes
  • 38.  Near Infrared Graphene Quantum Dots-Based Two-Photon Nanoprobe for Direct Bioimaging of Endogenous Ascorbic Acid in Living Cells

    LL, Feng; YX, Wu; DL, Zhang; XX, Hu; J, Zhang; P, Wang; ZL, Song; XB, Zhang; WH, Tan.

    Analytical Chemistry, 4077-4084. DOI: 10.1021/acs.analchem.6b04943,[2017]>> Fulltext Link

    Near Infrared Graphene Quantum Dots-Based Two-Photon Nanoprobe for Direct Bioimaging of Endogenous Ascorbic Acid in Living Cells
  • 39.  Nucleic acid-functionalized transition metal nanosheets for biosensing applications

    Mo, LT; Li, J; Liu, QL; Qiu, LP; Tan, WH.

    Biosensors and Bioelectronics, 201–211.DOI: 10.1016/j.bios.2016.03.044,[2017]>> Fulltext Link

    Nucleic acid-functionalized transition metal nanosheets for biosensing applications
  • 40.  Graphitic nanocapsules: design, synthesis and bioanalytical applications

    D, D; Xu, YT; Zou, YX; Chen, L; Chen, Zh; Tan, WH.

    Nanoscale, online. DOI: 10.1039/C7NR02587D,[2017]>> Fulltext Link

    Graphitic nanocapsules: design, synthesis and bioanalytical applications
  • 41.  Aptamer-assembled nanomaterials for fluorescent sensing and imaging

    Lu,DQ; He, L; Zhang, G; Lv, AP; Wang, RW; Zhang, XB; Tan, WH.

    Nanophotonics, 109–121. DOI: 10.1515/nanoph-2015-0145,[2017]>> Fulltext Link

    Aptamer-assembled nanomaterials for fluorescent sensing and imaging
  • 42.  一种检测胰腺导管癌的核酸适配体、试剂盒及方法

    谭蔚泓、赵子龙、武晓秋、叶茂、白华荣

    发明专利, 201510066356X,[2017]>> Fulltext Link

  • 43.  A Smart Photosensitizer-Manganese Dioxide Nanosystem for Enhanced Photodynamic Therapy by Reducing Glutathione Levels in Cancer Cells

    Fan, HH; Yan, GB; Zhao, ZL; Hu, XX; Zhang, WH; Liu, H; Fu, XY; Fu, T; Zhang, XB; Tan, WH

    Angewandte Chemie International Edition, 5477-5482.DOI: 10.1002/ange.201510748,[2016]>> Fulltext Link

    A Smart Photosensitizer-Manganese Dioxide Nanosystem for Enhanced Photodynamic Therapy by Reducing Glutathione Levels in Cancer Cells
  • 44.  Intercellular Connections Related to Cell-Cell Crosstalk Specifically Recognized by an Aptamer

    Zhang, N ; Bing, T ; Shen, LY ; Song, RS ; Wang, LL ; Liu, XJ ; Liu, MR ; Li, J ; Tan, WH; Shangguan, DH

    Angewandte Chemie International Edition, 3914-3918.DOI: 10.1002/anie.201510786,[2016]>> Fulltext Link

    Intercellular Connections Related to Cell-Cell Crosstalk Specifically Recognized by an Aptamer
  • 45.  Functional nucleic acid-based hydrogels for bioanalytical and biomedical applications

    Li, J; Mo, LT; Lu, CH; Fu, T; Yang, HH; Tan, WH

    Chemical Society Reviews, 1410-1431.DOI: 10.1039/C5CS00586H,[2016]>> Fulltext Link

    Functional nucleic acid-based hydrogels for bioanalytical and biomedical applications
  • 46.  Using modified aptamers for site specific protein-aptamer conjugations

    Wang, RW; Lu, DQ; Bai, HR; Jin, C; Yan, GB; Ye, M; Qiu, LP; Chang, RS; Cui, C; Liang, H; Tan, WH

    Chemical Science, 2157-2161.DOI: 10.1039/C5SC02631H,[2016]>> Fulltext Link

    Using modified aptamers for site specific protein-aptamer conjugations
  • 47.  A unique approach toward near-infrared fluorescent probes for bioimaging with remarkably enhanced contrast

    Gong, YJ; Zhang, XB; Mao, GJ; Su, L; Meng, HM; Tan, WH; Feng, SL; Zhang, GS

    Chemical Science, 2275-2285.DOI: 10.1039/C5SC04014K,[2016]>> Fulltext Link

    A unique approach toward near-infrared fluorescent probes for bioimaging with remarkably enhanced contrast
  • 48.  Catalytic self-assembly of a DNA dendritic complex for efficient gene silencing

    Lv, YF; Peng, RZ; Zhou, Y; Zhang, XB; Tan, WH

    Chemical Communications, 1413-1415.DOI: 10.1039/C5CC06937H,[2016]>> Fulltext Link

    Catalytic self-assembly of a DNA dendritic complex for efficient gene silencing
  • 49.  A FRET-based ratiometric two-photon fluorescent probe for dual-channel imaging of nitroxyl in living cells and tissues

    Zhu, XY; Xiong, MY; Liu, HW; Mao, GJ; Zhou, LY; Zhang, J; Hu, XX; Zhang, XB; Tan, WH

    Chemical Communications, 733-736.DOI: 10.1039/C5CC08695G,[2016]>> Fulltext Link

    A FRET-based ratiometric two-photon fluorescent probe for dual-channel imaging of nitroxyl in living cells and tissues
  • 50.  A membrane-anchored fluorescent probe for detecting K+ in the cell microenvironment

    Xiong, MY; Zhu, HJ; Rong, QM; Yang, C; Qiu, LP; Zhang, XB; Tan, WH

    Chemical Communications, 4679-4682.DOI: 10.1039/C6CC00192K,[2016]>> Fulltext Link

    A membrane-anchored fluorescent probe for detecting K+ in the cell microenvironment
  • 51.  Quench-Shield Ratiometric Upconversion Luminescence Nanoplatform for Biosensing

    Wu, YX; Zhang, XB; Zhang, DL; Zhang, CC; Li, JB; Wu, Y; Song, ZL; Yu, RQ; Tan, WH

    Analytical Chemistry, 1639-1646.DOI: 10.1021/acs.analchem.5b03573,[2016]>> Fulltext Link

    Quench-Shield Ratiometric Upconversion Luminescence Nanoplatform for Biosensing
  • 52.  Biostable L-DNAzyme for Sensing of Metal Ions in Biological Systems

    Cui, L; Peng, RZ; Fu, T; Zhang, XB; Wu, CC; Chen, HP; Liang, H; Yang, CJ; Tan, WH

    Analytical Chemistry, 1850-1855.DOI: 10.1021/acs.analchem.5b04170,[2016]>> Fulltext Link

    Biostable L-DNAzyme for Sensing of Metal Ions in Biological Systems
  • 53.  Modulating the Morphology of Gold Graphitic Nanocapsules for Plasmon Resonance-Enhanced Multimodal Imaging

    Lai, XF; Zou, YX; Wang, SS; Zheng, MJ; Hu, XX; Liang, H; Xu, YT; Wang, XW; Ding, D; Chen, L; Chen, Z; Tan, WH

    Analytical Chemistry, 5385-5391.DOI: 10.1021/acs.analchem.6b00714,[2016]>> Fulltext Link

    Modulating the Morphology of Gold Graphitic Nanocapsules for Plasmon Resonance-Enhanced Multimodal Imaging
  • 54.  Stable Graphene-Isolated-Au-Nanocrystal for Accurate and Rapid Surface Enhancement Raman Scattering Analysis

    Zhang, Y; Zou, YX; Liu, F; Xu,YT; Wang, XW; Li, YJ; Liang, H; Chen, L; Chen, Z; Tan, WH

    Analytical Chemistry, 10611–10616.DOI: 10.1021/acs.analchem.6b02958,[2016]>> Fulltext Link

    Stable Graphene-Isolated-Au-Nanocrystal for Accurate and Rapid Surface Enhancement Raman Scattering Analysis
  • 55.  Screening and identification of DNA aptamers toward Schistosoma japonicum eggs via SELEX

    Long, YQ; Qin, ZQ; Duan, ML; Li, SZ; Wu, XQ; Lin, W; Li, JL; Zhao, ZL; Liu, J; Xiong, DH; Huang, Y; Hu, XX; Yang, C; Ye, M; Tan, WH

    Scientific Reports, 24986.DOI:10.1038/srep24986,[2016]>> Fulltext Link

    Screening and identification of DNA aptamers toward Schistosoma japonicum eggs via SELEX
  • 56.  A label-free DNAzyme fluorescence biosensor for amplified detection of Pb2+-based on cleavage-induced G-quadruplex formation

    Fu, T; Ren, SL; Gong, L; Meng, HM; Cui, L; Kong, RM; Zhang, XB; Tan, WH

    Talanta, 302-306.DOI:10.1016/j.talanta.2015.10.004,[2016]>> Fulltext Link

    A label-free DNAzyme fluorescence biosensor for amplified detection of Pb2+-based on cleavage-induced G-quadruplex formation
  • 57.  Selection and characterization of DNA aptamer for metastatic prostate cancer recognition and tissue imaging

    Duan, ML; Long, YQ; Yang, C; Wu, XQ; Sun, Y; Li, JL; Hu, XX; Lin, W; Han, DM; Zhao, YF; Liu, J; Ye, M; Tan, WH

    Oncotarget, 36436-36446.DOI: 10.18632/oncotarget.9262,[2016]>> Fulltext Link

    Selection and characterization of DNA aptamer for metastatic prostate cancer recognition and tissue imaging
  • 58.  ICG-Conjugated magnetic graphene oxide for dual photothermal and photodynamic therapy

    Ocsoy, I; Isiklan, N; Cansiz, S; Ouml; zdemir, N; Tan, WH

    RSC Advances, 30285-30292.DOI: 10.1039/C6RA06798K,[2016]>> Fulltext Link

    ICG-Conjugated magnetic graphene oxide for dual photothermal and photodynamic therapy
  • 59.  Elucidating the cellular uptake mechanism of aptamer-functionalized graphene-isolated-Au-nanocrystals with dual-modal imaging

    Wang, SS; Liu, ZK; Zou, YX; Lai, XF; Ding, D; Chen, L; Zhang, LQ; Wu, Y; Chen, Z; Tan, WH

    Analyst, 3337-3342.DOI: 10.1039/C6AN00483K,[2016]>> Fulltext Link

    Elucidating the cellular uptake mechanism of aptamer-functionalized graphene-isolated-Au-nanocrystals with dual-modal imaging
  • 60.  A two-photon fluorescent probe for bio-imaging of formaldehyde in living cells and tissues

    Li, JB; Wang, QQ; Yuan, L; Wu, YX; Hu, XX; Zhang, XB; Tan, WH

    Analyst, 3395-3402.DOI: 10.1039/C6AN00473C,[2016]>> Fulltext Link

    A two-photon fluorescent probe for bio-imaging of formaldehyde in living cells and tissues
  • 61.  Cancer biomarker discovery using DNA aptamers

    Jin, C; Qiu, LP; Li, J; Fu, T; Zhang, XB; Tan, WH

    Analyst, 461-466.DOI: 10.1039/C5AN01918D,[2016]>> Fulltext Link

    Cancer biomarker discovery using DNA aptamers
  • 62.  Versatile surface engineering of porous nanomaterials with bioinspired polyphenol coatings for targeted and controlled drug delivery

    Li, J; Wu, SX; Wu, CC; Qiu, LP; Zhu, GZ; Cui, C; Liu, Y; Hou, WJ; Wang, YY; Zhang, LQ; Teng, IT; Yang, HH; Tan, WH

    Nanoscale, 8600-8606.DOI: 10.1039/C6NR00600K,[2016]>> Fulltext Link

    Versatile surface engineering of porous nanomaterials with bioinspired polyphenol coatings for targeted and controlled drug delivery
  • 63.  Simultaneous tracking of drug molecules and carriers using aptamer-functionalized fluorescent superstable gold nanorod-carbon nanocapsules during thermo-chemotherapy

    Wang, XW; Gao, W ; Fan, HH; Ding, D; Lai, XF; Zou, YX; Chen, L; Chen, Z; Tan, WH

    Nanoscale, 7942-7948.DOI: 10.1039/C6NR00369A,[2016]>> Fulltext Link

    Simultaneous tracking of drug molecules and carriers using aptamer-functionalized fluorescent superstable gold nanorod-carbon nanocapsules during thermo-chemotherapy
  • 64.  Fabrication of ultrathin Zn(OH)(2) nanosheets as drug carriers

    Cai, R; Yang, D; Wu, J; Zhang, LQ; Wu, CC; Chen, XG; Wang, YY; Wan, S; Hou, FW; Yan, QY; Tan, WH

    Nano Research, 2520-2530.DOI: 10.1007/s12274-016-1138-2,[2016]>> Fulltext Link

    Fabrication of ultrathin Zn(OH)(2) nanosheets as drug carriers
  • 65.  Stable and unique graphitic Raman internal standard nanocapsules for surface-enhanced Raman spectroscopy quantitative analysis

    Zou, YX; Chen, L; Song, ZL; Ding, D; Chen, YQ; Xu, YT; Wang, SS; Lai, XF; Zhang, Y; Sun, Y; Chen, Z; Tan, WH

    Nano Research, 1418-1425.DOI:10.1007/s12274-016-1037-6,[2016]>> Fulltext Link

    Stable and unique graphitic Raman internal standard nanocapsules for surface-enhanced Raman spectroscopy quantitative analysis
  • 66.  Overexpression of WDR79 in non-small cell lung cancer is linked to tumour progression

    Sun, Y; Yang, C; Chen, JY; Song, X; Li, Z; Duan, ML; Li, JL; Hu, XX; Wu, KP; Yan, GB; Yang, C; Liu, J; Tan, WH; Ye, M

    Journal of Cellular and Molecular Medicine, 698-709.DOI:10.1111/jcmm.12759,[2016]>> Fulltext Link

    Overexpression of WDR79 in non-small cell lung cancer is linked to tumour progression
  • 67.  Three dimensional multipod superstructures based on Cu(OH)(2) as a highly efficient nanozyme

    Cai, R; Yang, D; Chen, XG; Huang, Y; Lyu, YF; He, JL; Shi, ML; Teng, IT; Wan, S; Hou, WJ; Tan, WH

    Journal of Materials Chemistry B, 4657-4661.DOI: 10.1039/C6TB01233G,[2016]>> Fulltext Link

    Three dimensional multipod superstructures based on Cu(OH)(2) as a highly efficient nanozyme
  • 68.  Generating Cell Targeting Aptamers for Nanotheranostics Using Cell-SELEX

    Lyu, YF; Chen, G; Shangguan, DH; Zhang, LQ; Wan, S; Wu, Y; Zhang, H; Duan, L; Liu, C; You, MX; Wang, J; Tan, WH

    Theranostics, 1440-1452.DOI:10.7150/thno.15666,[2016]>> Fulltext Link

    Generating Cell Targeting Aptamers for Nanotheranostics Using Cell-SELEX
  • 69.  A cascade reaction network mimicking the basic functional steps of acquired immune response

    Han, D; Wu, CC; You, MX; Zhang, T; Wan, S; Chen, T; Qiu, LP; Zheng, Z; Liang, H; Tan, WH

    Nature Chemistry, 835-841.DOI:10.1038/nchem.2325,[2015]>> Fulltext Link

    A cascade reaction network mimicking the basic functional steps of acquired immune response
  • 70.  A Nonenzymatic Hairpin DNA Cascade Reaction Provides High Signal Gain of mRNA Imaging inside Live Cells

    Wu, CC ; Cansiz, S ; Zhang, LQ ; Teng, IT ; Qiu, LP ; Li, J ; Liu, Y ; Zhou, CS ; Hu, R ; Zhang, T ; Cui, C; Cui, L ; Tan, WH

    Journal of the American Chemical Society, 4900-4903.DOI: 10.1021/jacs.5b00542,[2015]>> Fulltext Link

    A Nonenzymatic Hairpin DNA Cascade Reaction Provides High Signal Gain of mRNA Imaging inside Live Cells
  • 71.  Programmable and Multiparameter DNA-Based Logic Platform For Cancer Recognition and Targeted Therapy

    You, MX ; Zhu, GZ ; Chen, T ; Donovan, MJ ; Tan, WH

    Journal of the American Chemical Society, 667-674. DOI: 10.1021/ja509263k,[2015]>> Fulltext Link

    Programmable and Multiparameter DNA-Based Logic Platform For Cancer Recognition and Targeted Therapy
  • 72.  Self-assembly of DNA Nanohydrogels with Controllable Size and Stimuli-responsive Property for Targeted Gene Therapy

    Li, J ; Zheng, C ; Cansiz, S ; Wu, CC ; Xu, JH ; Cui, C ; Liu, Y ; Hou, WJ ; Wang, YY ; Zhang, LQ ; Teng, IT ; Yang, HH ; Tan, WH

    Journal of the American Chemical Society, 1412-1415. DOI: 10.1021/ja512293f,[2015]>> Fulltext Link

    Self-assembly of DNA Nanohydrogels with Controllable Size and Stimuli-responsive Property for Targeted Gene Therapy
  • 73.  Evolution of Functional Six-Nucleotide DNA

    Zhang, LQ ; Yang, ZY ; Sefah, K ; Bradley, KM ; Hoshika, S ; Kim, MJ ; Kim, HJ ; Zhu, GZ ; Jimenez, E ; Cansiz, S ; Teng, IT ; Champanhac, C ; McLendon, C ; Liu, C ; Zhang, W ; Gerloff, DL ; Hu

    Journal of the American Chemical Society, 6734-6737 .DOI: 10.1021/jacs.5b02251,[2015]>> Fulltext Link

    Evolution of Functional Six-Nucleotide DNA
  • 74.  Ionic Functionalization of Hydrophobic Colloidal Nanoparticles To Form Ionic Nanoparticles with Enzymelike Properties

    Liu Y; Purich DL; Wu CC; Wu Y; Chen T; Cui C; Zhang LQ; Cansiz S; Hou WJ; Wang YY; Yang SH; Tan WH

    Journal of the American Chemical Society, 14952-14958.DOI: 10.1021/jacs.5b08533,[2015]>> Fulltext Link

    Ionic Functionalization of Hydrophobic Colloidal Nanoparticles To Form Ionic Nanoparticles with Enzymelike Properties
  • 75.  Single Nanoparticle to 3D Supercage: Framing for an Artificial Enzyme System

    Cai, R ; Yang, D ; Peng, SJ ; Chen, XG ; Huang, Y ; Liu, Y ; Hou, WJ ; Yang, SY ; Liu, ZB ; Tan, WH

    Journal of the American Chemical Society, 13957-13963.DOI: 10.1021/jacs.5b09337,[2015]>> Fulltext Link

    Single Nanoparticle to 3D Supercage: Framing for an Artificial Enzyme System
  • 76.  Phase Transfer and Surface Biofunctionalization of Hydrophobic Nanoparticles Using Janus DNA Tetrahedron Nanostructures

    Li, J ; Hong, CY ; Wu, SX ; Liang, H ; Wang, LP ; Huang, GM ; Chen, X ; Yang, HH ; Shangguan, DH ; Tan, WH

    Journal of the American Chemical Society, 11210-11213.DOI: 10.1021/jacs.5b05650,[2015]>> Fulltext Link

    Phase Transfer and Surface Biofunctionalization of Hydrophobic Nanoparticles Using Janus DNA Tetrahedron Nanostructures
  • 77.  Rationally designed molecular beacons for bioanalytical and biomedical applications

    Zheng, J ; Yang, RH ; Shi, ML ; Wu, CC ; Fang, XH ; Li, YH ; Li, JH ; Tan, WH

    Chemical Society Reviews, 3036-3055..DOI: 10.1039/C5CS00020C,[2015]>> Fulltext Link

    Rationally designed molecular beacons for bioanalytical and biomedical applications
  • 78.  A smart DNAzyme-MnO2 nanosystem for efficient gene silencing

    Fan, HH ; Zhao, ZL ; Yan, GB ; Zhang, XB ; Yang, C ; Meng, HM ; Chen, Z ; Liu, H ; Tan, WH

    Angewandte Chemie International Edition, 4801-4805.DOI: 10.1002/anie.201411417,[2015]>> Fulltext Link

    A smart DNAzyme-MnO2 nanosystem for efficient gene silencing
  • 79.  Direct Visualization of Walking Motions of Photocontrolled Nanomachine on the DNA Nanostructure

    Yang, YY ; Goetzfried, MA ; Hidaka, K ; You, MX ; Tan, WH ; Sugiyama, H ; Endo, M

    ACS Nano, 6672-6676.DOI: 10.1021/acs.nanolett.5b02502,[2015]>> Fulltext Link

    Direct Visualization of Walking Motions of Photocontrolled Nanomachine on the DNA Nanostructure
  • 80.  Preparation and biomedical applications of programmable and multifunctional DNA nanoflowers

    Lv, YF ; Hu, R ; Zhu, GZ ; Zhang, XB ; Mei, L ; Liu, QL ; Qiu, LP ; Wu, CC ; Tan, WH

    Nature Protocol, 1508-1524.DOI:10.1038/nprot.2015.078,[2015]>> Fulltext Link

    Preparation and biomedical applications of programmable and multifunctional DNA nanoflowers
  • 81.  Cell-Targeted, Size-Photocontrollable, Nuclear-Uptake Nanodrug Delivery System for Drug-Resistant Cancer Therapy

    Qiu, LP ; Chen, T ; Ocsoy, I ; Yasun, E ; Wu, CC ; Zhu, GZ ; You, MX ; Han, D ; Jiang, JH ; Yu, RQ ; Tan, WH

    Nano Letters, 457-463. DOI: 10.1021/nl503777s,[2015]>> Fulltext Link

    Cell-Targeted, Size-Photocontrollable, Nuclear-Uptake Nanodrug Delivery System for Drug-Resistant Cancer Therapy
  • 82.  Entropy beacon: a hairpin-free DNA amplification strategy for efficient detection of nucleic acids

    Lv, YF ; Cui, L ; Peng, RZ ; Zhao, ZL ; Qiu, LP ; Chen, HP ; Jin, C ; Zhang, XB ; Tan, WH

    Analytical Chemistry, 11714-11720 .DOI: 10.1021/acs.analchem.5b02654,[2015]>> Fulltext Link

    Entropy beacon: a hairpin-free DNA amplification strategy for efficient detection of nucleic acids
  • 83.  Localizable and Photoactivatable Fluorophore for Spatiotemporal Two-Photon Bioimaging

    Zhou, LY ; Zhang, XB ; Lv, YF ; Yang, C ; Lu, DQ ; Wu, Y ; Chen, Z ; Liu, QL ; Tan, WH

    Analytical Chemistry, 5626-5631. DOI: 10.1021/acs.analchem.5b00691,[2015]>> Fulltext Link

    Localizable and Photoactivatable Fluorophore for Spatiotemporal Two-Photon Bioimaging
  • 84.  Multiple Functional Nanoprobe for Contrast-Enhanced Bimodal Cellular Imaging and Targeted Therapy

    Meng, HM ; Lu, LM ; Zhao, XH ; Chen, Z ; Zhao, ZL ; Yang, C ; Zhang, XB ; Tan, WH

    Analytical Chemistry, 4448-4454. DOI: 10.1021/acs.analchem.5b00337,[2015]>> Fulltext Link

    Multiple Functional Nanoprobe for Contrast-Enhanced Bimodal Cellular Imaging and Targeted Therapy
  • 85.  Through-Bond Energy Transfer-Based Ratiometric Two-Photon Probe for Fluorescent Imaging of Pd2+ Ions in Living Cells and Tissues

    Zhou, LY ; Wang, QQ ; Zhang, XB ; Tan, WH

    Analytical Chemistry, 4503-4507. DOI: 10.1021/acs.analchem.5b00505,[2015]>> Fulltext Link

    Through-Bond Energy Transfer-Based Ratiometric Two-Photon Probe for Fluorescent Imaging of Pd2+ Ions in Living Cells and Tissues
  • 86.  A DNAzyme-Based ELISA for Protein Enzyme-Free Immunoassay of Multiple Analytes

    Hu, R ; Liu, T ; Zhang, XB ; Yang, YH ; Chen, T ; Wu, CC ; Liu, Y ; Zhu, GZ ; Huan, SY ; Fu, T ; Tan, WH

    Analytical Chemistry, 7746-7753.DOI: 10.1021/acs.analchem.5b01323,[2015]>> Fulltext Link

    A DNAzyme-Based ELISA for Protein Enzyme-Free Immunoassay of Multiple Analytes
  • 87.  Efficient Two-Photon Fluorescent Probe with Red Emission for Imaging of Thiophenols in Living Cells and Tissues

    Liu, HW ; Zhang, XB ; Zhang, J ; Wang, QQ ; Hu, XX ; Wang, P ; Tan, WH

    Analytical Chemistry, 8896–8903. DOI: 10.1021/acs.analchem.5b02021,[2015]>> Fulltext Link

    Efficient Two-Photon Fluorescent Probe with Red Emission for Imaging of Thiophenols in Living Cells and Tissues
  • 88.  Efficient Two-Photon Fluorescent Probe for Nitroreductase Detection and Hypoxia Imaging in Tumor Cells and Tissues

    Zhang, J ; Liu, HW ; Hu, XX ; Li, J ; Liang, LH ; Zhang, XB ; Tan, WH

    Analytical Chemistry, 11832-11839.DOI: 10.1021/acs.analchem.5b03336,[2015]>> Fulltext Link

    Efficient Two-Photon Fluorescent Probe for Nitroreductase Detection and Hypoxia Imaging in Tumor Cells and Tissues
  • 89.  Using DNA Aptamer Probe for Immunostaining of Cancer Frozen Tissues

    Pu, Y ; Liu, ZX ; Lu, Y ; Yuan, P ; Liu, J ; Yu, B ; Wang, GD ; Yang, CJ ; Liu, HX ; Tan, WH

    Analytical Chemistry, 1919-1924.DOI: 10.1021/ac504175h,[2015]>> Fulltext Link

    Using DNA Aptamer Probe for Immunostaining of Cancer Frozen Tissues
  • 90.  DNAzyme-based biosensors and nanodevices

    Gong, L ; Zhao, ZL ; Lv, YF ; Huan, SY ; Fu, T ; Zhang, XB ; Shen, GL ; Yu, RQ

    Chemical Communications, 979-995.DOI: 10.1039/C4CC06855F,[2015]>> Fulltext Link

    DNAzyme-based biosensors and nanodevices
  • 91.  Ag nanocluster-based label-free catalytic and molecular beacons for amplified biosensing

    Gong, L ; Kuai, HL ; Ren, SL ; Zhao, XH ; Huan, SY ; Zhang, XB ; Tan, WH

    Chemical Communications, 12095-12098.DOI: 10.1039/C5CC04442A,[2015]>> Fulltext Link

    Ag nanocluster-based label-free catalytic and molecular beacons for amplified biosensing
  • 92.  A novel AgNP/DNA/TPdye Conjugate-based Two-photon Nanoprobe for GSH Imaging in Cell Apoptosis of Cancer Tissue

    Tang, Q ; Wang, NN ; Zhou, FL ; Deng, T ; Zhang, SB ; Li, JS ; Yang, RH ; Zhong, WW ; Tan, WH

    Chemical Communications, 16810-16812.DOI: 10.1039/C5CC06471F,[2015]>> Fulltext Link

    A novel AgNP/DNA/TPdye Conjugate-based Two-photon Nanoprobe for GSH Imaging in Cell Apoptosis of Cancer Tissue
  • 93.  Enzymatic cleavage and mass amplification strategy for small molecule detection using aptamer-based fluorescence polarization biosensor

    Kang, LP ; Yang, B ; Zhang, XB ; Cui, L ; Meng, HM ; Mei, L ; Wu, CC ; Ren, SL ; Tan, WH

    Analytica Chimica Acta, 91-96.DOI: 10.1016/j.aca.2015.03.030,[2015]>> Fulltext Link

    Enzymatic cleavage and mass amplification strategy for small molecule detection using aptamer-based fluorescence polarization biosensor
  • 94.  An efficient ratiometricfluorescent probe for tracking dynamic changes in lysosomal pH

    Wang, QQ ; Zhou, LY ; Qiu, LP ; Lu, DQ ; Wu, YX ; Zhang, XB

    Analytica Chimica Acta, 5563–5569.DOI: 10.1039/C5AN00683J,[2015]>> Fulltext Link

    An efficient ratiometricfluorescent probe for tracking dynamic changes in lysosomal pH
  • 95.  Self-Assembled DNA Immunonanoflowers as Multivalent CpG Nanoagents

    Zhang, LQ; Zhu, GZ; Mei, L; Wu, CC; Qiu, LP; Cui, C; Liu, Y; Teng, IT; Tan, WH

    ACS Applied Materials & Interfaces, 24069-24074.DOI: 10.1021/acsami.5b06987,[2015]>> Fulltext Link

    Self-Assembled DNA Immunonanoflowers as Multivalent CpG Nanoagents
  • 96.  Nuclease-resistant synthetic drug-DNA adducts: programmable drug-DNA conjugation for targeted anticancer drug delivery

    Zhu, GZ ; Cansiz, S ; You, MX ; Qiu, LP ; Han, D ; Zhang, LQ ; Mei, L ; Fu, T ; Chen, Z ; Tan, WH

    NPG Asia Materials, e169.DOI:10.1038/am.2015.19.,[2015]>> Fulltext Link

    Nuclease-resistant synthetic drug-DNA adducts: programmable drug-DNA conjugation for targeted anticancer drug delivery
  • 97.  Self-assembled multifunctional DNA nanoflowers for the circumvention of multidrug resistance in targeted anticancer drug delivery

    Mei, L; Zhu, GZ; Qiu, LP; Wu, CC; Chen, HP; Liang, H ; Cansiz, S ; Lv, YF ; Zhang, XB ; Tan, WH

    Nano Research, 3447-3460. DOI: 10.1007/s12274-015-0841-8,[2015]>> Fulltext Link

    Self-assembled multifunctional DNA nanoflowers for the circumvention of multidrug resistance in targeted anticancer drug delivery
  • 98.  A Synthetic Aptamer-Drug Adduct for Targeted Liver Cancer Therapy

    Le Trinh, T ; Zhu, GZ ; Xiao, XL ; Puszyk, W ; Sefah, K ; Wu, QF ; Tan, WH; Liu, C

    Plos One, e0136673. DOI:10.1371/journal.pone.0136673,[2015]>> Fulltext Link

    A Synthetic Aptamer-Drug Adduct for Targeted Liver Cancer Therapy
  • 99.  Fluorescent nanosensor for probing histone acetyltransferase activity based on acetylation protection and magnetic graphitic nanocapsules

    Han, YT; Li, P; Xu, YT; Li, H; Song, ZL; Nie, Z; Chen, Z; Yao, SZ

    Small, 877-885.DOI: 10.1002/smll.201401989,[2015]>> Fulltext Link

    Fluorescent nanosensor for probing histone acetyltransferase activity based on acetylation protection and magnetic graphitic nanocapsules
  • 100.  Nucleic Acid Aptamer-Mediated Drug Delivery for Targeted Cancer Therapy

    Zhu, HJ ; Li, J ; Zhang, XB ; Ye, M ; Tan, WH

    ChemMedChem, 39-45. DOI: 10.1002/cmdc.201402312,[2015]>> Fulltext Link

    Nucleic Acid Aptamer-Mediated Drug Delivery for Targeted Cancer Therapy
  • 101.  BSA modification to reduce CTAB induced nonspecificity and cytotoxicity of aptamer-conjugated gold nanorods

    Yasun, E; Li, CM; Barut, I; Janvier, D; Qiu, LP; Cui, C; Tan, WH

    Nanoscale, 10240-10248.DOI: 10.1039/C5NR01704A,[2015]>> Fulltext Link

    BSA modification to reduce CTAB induced nonspecificity and cytotoxicity of aptamer-conjugated gold nanorods
  • 102.  STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation

    Ye, M ; Tang, YN ; Tang, SJ ; Liu, J ; Wu, KP ; Yao, S ; Sun, Y ; Zhou, L ; Deng, TG ; Chen, Y ; Huang, CH ; Tan, WH

    Oncotarget, 34718-34731. DOI: 10.18632/oncotarget.5303,[2015]>> Fulltext Link

    STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation
  • 103.  DNA aptamer selected against pancreatic ductal adenocarcinoma for in vivo imaging and clinical tissue recognition

    Wu, XQ ; Zhao, ZL ; Bai, HR ; Fu, T ; Yang, C ; Hu, XX ; Liu, QL ; Champanhac, C ; Teng, IT ; Ye, M ; Tan, WH

    Theranostics, 985-994. DOI:10.7150/thno.11938,[2015]>> Fulltext Link

    DNA aptamer selected against pancreatic ductal adenocarcinoma for in vivo imaging and clinical tissue recognition
  • 104.  STIP overexpression confers oncogenic potential to human non-small cell lung cancer cells by regulating cell cycle and apoptosis

    Tang, YN ; Yan, GB ; Song, X ; Wu, KP; Li, Z; Yang, C; Deng, TG; Sun, Y; Hu, XX; Yang, C; Bai, HR; Li, H; Tan, WH; Ye, M; Liu, J

    Journal of Cellular and Molecular Medicine, 2806-2817.DOI: 10.1111/jcmm.12670,[2015]>> Fulltext Link

    STIP overexpression confers oncogenic potential to human non-small cell lung cancer cells by regulating cell cycle and apoptosis
  • 105.  Fabrication of superstable gold nanorod-carbon nanocapsule as a molecule loading material

    Wei Gao, Xuewei Wang, Huanhuan Fan, Zhiling Song, Xiaofang Lai, Zhuo Chen*, Weihong Tan*

    Science Bulletin, 1101-1107. DOI:10.1007/s11434-015-0814-z,[2015]>> Fulltext Link

    Fabrication of superstable gold nanorod-carbon nanocapsule as a molecule loading material
  • 106.  Fabrication of GO/magnetic graphitic nanocapsule/TiO2 assemblies as efficient and recyclable photocatalysts

    Cheng, ZQ ; Ding, D ; Nie, XK ; Xu, YT ; Song, ZL ; Fu, T ; Chen, Z ; Tan, WH

    Science China-Chemistry, 1131-1136 DOI: 10.1007/s11426-015-5419-5,[2015]>> Fulltext Link

    Fabrication of GO/magnetic graphitic nanocapsule/TiO2 assemblies as efficient and recyclable photocatalysts
  • 107.  Cell-SELEX based aptamer-conjugated nanomaterials for cancer diagnosis and therapy

    Meng, HM ; Fu, T ; Zhang, XB ; Tan, WH

    National Science Review, 71-84.DOI: 10.1093/nsr/nwv001,[2015]>> Fulltext Link

    Cell-SELEX based aptamer-conjugated nanomaterials for cancer diagnosis and therapy
  • 108.  Study of the Function of G-Rich Aptamers Selected for Lung Adenocarcinoma

    Hu, J ; Zhao, ZL; Liu, QL; Ye, M; Hu, BQ; Wang, J; Tan, WH

    Chemistry-An Asian Journal, 1519-1525. DOI: 10.1002/asia.201500187,[2015]>> Fulltext Link

    Study of the Function of G-Rich Aptamers Selected for Lung Adenocarcinoma
  • 109.  DNA Aptamer Based Nanodrugs: Molecular Engineering for Efficiency

    Cansiz, S; Zhang, LQ; Wu, CC; Wu, Y; Teng, IT; Hou, WJ; Wang, YY; Wan, SO; Cai, R; Jin, C; Liu, QL; Tan, WH

    Chemistry-An Asian Journal, 2084-2094.DOI: 10.1002/asia.201500434View/save citation,[2015]>> Fulltext Link

    DNA Aptamer Based Nanodrugs: Molecular Engineering for Efficiency
  • 110.  Aptamer CaCO3 Nanostructures: A Facile, pH-Responsive, Specific Platform for Targeted Anticancer Theranostics

    Zhou, CS; Chen, T; Wu, CC; Zhu, GZ; Qiu, LP; Cui, C; Hou, WJ; Tan, WH

    Chemistry-An Asian Journal, 166-171.DOI: 10.1002/asia.201403115,[2015]>> Fulltext Link

    Aptamer CaCO3 Nanostructures: A Facile, pH-Responsive, Specific Platform for Targeted Anticancer Theranostics
  • 111.  一种检测赭曲霉素A的胶体金免疫试剂盒及其制备方法

    常荣山、谭蔚泓

    发明专利, ZL 201410031991X,[2015]>> Fulltext Link

  • 112.  一种核酸适配体制备治疗多发性骨髓瘤的药物或制品的用途

    刘静、谭蔚泓、叶茂、宋建辉、戴红娟

    发明专利, ZL 2013103430098,[2015]>> Fulltext Link

  • 113.  一种具有光磁双重加密功能的纳米材料及其制备方法和应用

    陈卓、聂祥坤、谭蔚泓、徐逸婷

    发明专利, ZL 2013104161898,[2015]>> Fulltext Link

  • 114.  一种金石墨烯复合纳米材料的制备方法

    陈卓、边霞、谭蔚泓

    发明专利, ZL 2013107295076,[2015]>> Fulltext Link

  • 115.  一种检测黄曲霉素B1的胶体金免疫试剂盒及其制备方法

    常荣山、谭蔚泓

    发明专利, ZL 2014100321591,[2015]>> Fulltext Link

  • 116.  一种核酸适配体及其制备治疗白血病的药物或制品的用途

    谭蔚泓、叶茂、刘静、宋建辉、戴红娟

    发明专利, ZL 2013103447281,[2015]>> Fulltext Link

  • 117.  基于核酸适配体的层析法检测试剂盒及其制备方法和检测方法

    谭蔚泓、常荣山、蒋健晖

    发明专利, ZL 2013100127510,[2015]>> Fulltext Link

  • 118.  DNA nanoflowers for multiplexed cellular imaging and traceable targeted drug delivery

    Hu, R; Zhang, XB; Zhao, ZL; Zhu, GZ; Chen, T; Fu, T; Tan, WH

    Angewandte Chemie International Edition, 5821-5826.DOI: 10.1002/ange.201400323,[2014]>> Fulltext Link

    DNA nanoflowers for multiplexed cellular imaging and traceable targeted drug delivery
  • 119.  Automated modular synthesis of aptamer-drug conjugates for targeted drug delivery

    Wang, RW; Zhu, GZ; Mei, L; Xie, Y; Ma, HB; Ye, M; Qing, FL; Tan, WH

    Journal of the American Chemical Society, 2731-2734.DOI: 10.1021/ja4117395,[2014]>> Fulltext Link

    Automated modular synthesis of aptamer-drug conjugates for targeted drug delivery
  • 120.  DNA "nano-claw": logic-based autonomous cancer targeting and therapy

    You, MX; Peng, L; Shao, N; Zhang, LQ; Qiu, LP; Cui, C; Tan, WH

    Journal of the American Chemical Society, 1256-1259.DOI: 10.1021/ja4114903,[2014]>> Fulltext Link

    DNA "nano-claw": logic-based autonomous cancer targeting and therapy
  • 121.  Molecular engineering of a TBET-based two-photon fluorescent probe for ratiometric imaging of living cells and tissues

    Zhou, LY; Zhang, XB; Wang, QQ; Lv, YF; Mao, GJ; Luo, AL; Wu, YX; Wu, Y; Zhang, J; Tan, WH

    Journal of the American Chemical Society, 9838-9841.DOI: 10.1021/ja504015t,[2014]>> Fulltext Link

    Molecular engineering of a TBET-based two-photon fluorescent probe for ratiometric imaging of living cells and tissues
  • 122.  Alkyne-functionalized superstable graphitic silver nanoparticles for Raman imaging

    Song, ZL; Chen, Z; Bian, X; Zhou, LY; Ding, D; Liang, H; Zou, YX; Wang, SS; Chen, L; Yang, C; Zhang, XB; Tan, WH

    Journal of the American Chemical Society, 13558-13561.DOI: 10.1021/ja507368z,[2014]>> Fulltext Link

    Alkyne-functionalized superstable graphitic silver nanoparticles for Raman imaging
  • 123.  Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet-Aptamer Nanoprobe

    Zhao, ZL; Fan, HH; Zhou, GF; Bai, HR; Liang, H; Wang, RW; Zhang, XB; Tan, WH

    Journal of the American Chemical Society, 11220-11223.DOI: 10.1021/ja5029364,[2014]>> Fulltext Link

    Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet-Aptamer Nanoprobe
  • 124.  Cell membrane-anchored biosensors for real-time monitoring of the cellular microenvironment

    Qiu, LP; Zhang, T; Jiang, JH; Wu, CC; Zhu, GZ; You, MX; Chen, XG; Zhang, LQ; Cui, C; Yu, RQ; Tan, WH

    Journal of the American Chemical Society, 13090-13093.DOI: 10.1021/ja5047389,[2014]>> Fulltext Link

    Cell membrane-anchored biosensors for real-time monitoring of the cellular microenvironment
  • 125.  DNA dendrimer: an efficient nanocarrier of functional nucleic acids for intracellular molecular sensing

    Meng, HM; Zhang, XB; Lv, YF; Zhao, ZL; Wang, NN; Fu, T; Fan, HH; Liang, H; Qiu, LP; Zhu, GZ; Tan, WH

    ACS Nano, 6171-6181.DOI: 10.1021/nn5015962,[2014]>> Fulltext Link

    DNA dendrimer: an efficient nanocarrier of functional nucleic acids for intracellular molecular sensing
  • 126.  Functional DNA-containing nanomaterials: cellular applications in biosensing, imaging, and targeted therapy

    Liang, H; Zhang, XB; Lv, YF; Gong, L; Wang, RW; Zhu, XY Yang, RH; Tan, WH

    Accounts of Chemical Research, 1891-1901.DOI: 10.1021/ar500078f,[2014]>> Fulltext Link

    Functional DNA-containing nanomaterials: cellular applications in biosensing, imaging, and targeted therapy
  • 127.  Multicolor fluorescent biosensor for multiplexed detection of DNA

    Hu, R; Liu, T; Zhang, XB; Huan, SY; Wu, CC; Fu, T; Tan, WH

    Analytical Chemistry, 5009-5016.DOI: 10.1021/ac500618v,[2014]>> Fulltext Link

    Multicolor fluorescent biosensor for multiplexed detection of DNA
  • 128.  Activatable two-photon fluorescence nanoprobe for bioimaging of glutathione in living cells and tissues

    Meng, HM; Jin, Z; Lv, YF; Yang, C; Zhang, XB; Tan, WH; Yu, RQ

    Analytical Chemistry, 12321-12326.DOI: 10.1021/ac503617n,[2014]>> Fulltext Link

    Activatable two-photon fluorescence nanoprobe for bioimaging of glutathione in living cells and tissues
  • 129.  Bispyrene-fluorescein hybrid based FRET cassette: a convenient platform toward ratiometric time-resolved probe for bioanalytical applications

    Wu, YX; Zhang, XB; Li, JB; Zhang, CC; Liang, H; Mao, GJ; Zhou, LY; Tan, WH; Yu, RQ

    Analytical Chemistry, 10389-10396.DOI: 10.1021/ac502863m,[2014]>> Fulltext Link

    Bispyrene-fluorescein hybrid based FRET cassette: a convenient platform toward ratiometric time-resolved probe for bioanalytical applications
  • 130.  A highly sensitive and reductant-resistant fluorescent probe for nitroxyl in aqueous solution and serum

    Mao, GJ; Zhang, XB; Shi, XL; Liu, HW; Wu, YX; Zhou, LY; Tan, WH; Yu, RQ

    Chemical Communications, 5790-5792.DOI: 10.1039/C4CC01440E,[2014]>> Fulltext Link

    A highly sensitive and reductant-resistant fluorescent probe for nitroxyl in aqueous solution and serum
  • 131.  A rhodamine-appended water-soluble conjugated polymer: an efficient ratiometric fluorescence sensing platform for intracellular metal-ion probing

    Wu, YX; Li, JB; Liang, LH; Lu, DQ; Zhang, J; Mao, GJ; Zhou, LY; Zhang, XB; Tan, WH; Shen, GL; Yu, RQ

    Chemical Communications, 2040-2042.DOI: 10.1039/C3CC48649D,[2014]>> Fulltext Link

    A rhodamine-appended water-soluble conjugated polymer: an efficient ratiometric fluorescence sensing platform for intracellular metal-ion probing
  • 132.  Fabrication of graphene-isolated-Au-nanocrystal nanostructures for multimodal cell imaging and photothermal-enhanced chemotherapy

    Bian, X; Song, ZL; Qian, Y; Gao, W; Cheng, ZQ; Chen, L; Liang, H; Ding, D; Nie, XK; Chen, Z; Tan, WH

    Scientific Reports, 6093.DOI:10.1038/srep06093,[2014]>> Fulltext Link

    Fabrication of graphene-isolated-Au-nanocrystal nanostructures for multimodal cell imaging and photothermal-enhanced chemotherapy
  • 133.  Nucleic acid aptamers for living cell analysis

    Xiong, XL; Lv, YF; Chen, T; Zhang, XB; Wang, KM; Tan, WH

    Annual Review of Analytical Chemistry, 405-426.DOI: 10.1146/annurev-anchem-071213-015944,[2014]>> Fulltext Link

    Nucleic acid aptamers for living cell analysis
  • 134.  Trifluoromethylated nucleic acid analogues capable of self-assembly through hydrophobic interactions

    Wang, RW; Wang, CM; Cao, Y; Zhu, Z; Yang, CY; Chen, JZ; Qing, FL; Tan, WH

    Chemical Science, 4076-4081.DOI: 10.1039/C4SC01162G,[2014]>> Fulltext Link

    Trifluoromethylated nucleic acid analogues capable of self-assembly through hydrophobic interactions
  • 135.  Gold nanorod-photosensitizer conjugate with extracellular pH-driven tumor targeting ability for photothermal/photodynamic therapy

    Wang, NN; Zhao, ZL; Lv, YF; Fan, HH; Bai, HR; Meng, HM; Long, YQ; Fu, T; Zhang, XB; Tan, WH

    Nano Research, 1291-1301.DOI: 10.1007/s12274-014-0493-0,[2014]>> Fulltext Link

    Gold nanorod-photosensitizer conjugate with extracellular pH-driven tumor targeting ability for photothermal/photodynamic therapy
  • 136.  Aptamer-conjugated nanomaterials for specific cancer cell recognition and targeted cancer therapy

    Liu, QL; Jin, C; Wang, YY; Fang, XH; Zhang, XB; Chen, Z; Tan, WH

    NPG Asia Materials, e95.DOI:10.1038/am.2014.12,[2014]>> Fulltext Link

    Aptamer-conjugated nanomaterials for specific cancer cell recognition and targeted cancer therapy
  • 137.  Magnetic-graphitic-nanocapsule template diacetylene assembly and photopolymerization for sensing and multicoded anti-counterfeiting

    Nie, XK; Xu, YT ; Song, ZL; Ding, D; Gao, F; Liang, H; Chen, L; Bian, X; Chen, Z; Tan, WH

    Nanoscale, 13097-13103.DOI: 10.1039/C4NR03837A,[2014]>> Fulltext Link

    Magnetic-graphitic-nanocapsule template diacetylene assembly and photopolymerization for sensing and multicoded anti-counterfeiting
  • 138.  Intelligent layered nanoflare: “lab-on-a-nanoparticle” for multiple DNA logic gate operations and efficient intracellular delivery

    Yang, B; Zhang, XB; Kang, LP; Huang, ZM; Shen, GL; Yu, RQ; Tan, WH

    Nanoscale, 8990-8996.DOI: 10.1039/C4NR01676A,[2014]>> Fulltext Link

    Intelligent layered nanoflare: “lab-on-a-nanoparticle” for multiple DNA logic gate operations and efficient intracellular delivery
  • 139.  An aggregated perylene-based broad-spectrum, efficient and label-free quencher for multiplexed fluorescent bioassays

    Liu, T; Hu, R; Lv, YF; Wu, Y; Liang, H; Huan, SY; Zhang, XB; Tan, WH; Yu, RQ

    Biosensors and Bioelectronics, 320-325.DOI:10.1016/j.bios.2014.02.083,[2014]>> Fulltext Link

    An aggregated perylene-based broad-spectrum, efficient and label-free quencher for multiplexed fluorescent bioassays
  • 140.  Hollow graphitic nanocapsules as efficient electrode materials for sensitive hydrogen peroxide detection

    Liu, WN; Ding, D; Song, ZL; Bian, X; Nie, XK; Zhang, XB; Chen, Z; Tan, WH

    Biosensors and Bioelectronics, 438-444.DOI:10.1016/j.bios.2013.08.023,[2014]>> Fulltext Link

    Hollow graphitic nanocapsules as efficient electrode materials for sensitive hydrogen peroxide detection
  • 141.  一种用于外周血中循环癌细胞的特异性捕获的装置及方法

    谭蔚泓、蒋健晖、陈卓、吕一帆

    发明专利, ZL 2012101931459,[2014]>> Fulltext Link

  • 142.  Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics

    Zhu, GZ ; Zheng, J; Song, EQ ; Donovan, M ; Zhang, KJ ; Liu, C ; Tan, WH

    Proceedings of the National Academy of Sciences, 7998-8003.DOI: 10.1073/pnas.1220817110,[2013]>> Fulltext Link

    Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics
  • 143.  Aptamers from cell-based selection for bioanalytical applications

    Tan, WH ; Donovan, MJ ; Jiang, JH

    Chemical Reviews, 2842-2862.DOI: 10.1021/cr300468w,[2013]>> Fulltext Link

    Aptamers from cell-based selection for bioanalytical applications
  • 144.  Building fluorescent DNA nanodevices on target living cell surfaces

    Zhu, GZ ; Zhang, SF ; Song, EQ ; Zheng, J; Hu, R ; Fang, XH ; Tan, WH

    Angewandte Chemie International Edition, 5490-5496.DOI: 10.1002/anie.201301439,[2013]>> Fulltext Link

    Building fluorescent DNA nanodevices on target living cell surfaces
  • 145.  Targeted bioimaging and photodynamic therapy nanoplatform using an aptamer-guided G-quadruplex DNA carrier and near-infrared light

    Yuan, Q; Wu, Y ; Wang, J ; Lu, DQ ; Zhao, ZL ; Liu, T ; Zhang, XB ; Tan, WH

    Angewandte Chemie International Edition, 13965-13969.DOI: 10.1002/anie.201305707,[2013]>> Fulltext Link

    Targeted bioimaging and photodynamic therapy nanoplatform using an aptamer-guided G-quadruplex DNA carrier and near-infrared light
  • 146.  A controlled-release nanocarrier with extracellular pH value driven tumor targeting and translocation for drug delivery

    Zhao, ZL ; Meng, HM ; Wang, NN ; Donovan, MJ ; Fu, T ; You, MX ; Chen, Z ; Zhang, XB ; Tan, WH

    Angewandte Chemie International Edition, 7487-7491.DOI: 10.1002/anie.201302557,[2013]>> Fulltext Link

    A controlled-release nanocarrier with extracellular pH value driven tumor targeting and translocation for drug delivery
  • 147.  A targeted, self-delivered, and photocontrolled molecular beacon for mRNA detection in living cells

    Qiu, LP ; Wu, CC ; You, MX ; Han, D ; Chen, T ; Zhu, GZ ; Jiang, JH ; Yu, RQ ; Tan, WH

    Journal of the American Chemical Society, 12952-12955.DOI: 10.1021/ja406252w,[2013]>> Fulltext Link

    A targeted, self-delivered, and photocontrolled molecular beacon for mRNA detection in living cells
  • 148.  Noncanonical self-assembly of multifunctional DNA nanoflowers for biomedical applications

    Zhu, GZ ; Hu, R ; Zhao, ZL ; Chen, Z ; Zhang, XB ; Tan, WH

    Journal of the American Chemical Society, 16438-16445.DOI: 10.1021/ja406115e,[2013]>> Fulltext Link

    Noncanonical self-assembly of multifunctional DNA nanoflowers for biomedical applications
  • 149.  A spherical nucleic acid platform based on self-assembled DNA biopolymer for high-performance cancer therapy

    Zheng, J; Zhu, GZ ; Li, YH ; Li, CM ; You, MX ; Chen, T ; Song, EQ ; Yang, RH ; Tan, WH

    ACS Nano, 6545-6554.DOI: 10.1021/nn402344v,[2013]>> Fulltext Link

    A spherical nucleic acid platform based on self-assembled DNA biopolymer for high-performance cancer therapy
  • 150.  Target-triggered cyclic assembly of DNA-protein hybrid nanowires for dual-amplified fluorescence anisotropy assay of small molecules

    Yang, B ; Zhang, XB ; Kang, LP ; Shen, GL ; Yu, RQ ; Tan, WH

    Analytical Chemistry, 11518-11523.DOI: 10.1021/ac402781g,[2013]>> Fulltext Link

    Target-triggered cyclic assembly of DNA-protein hybrid nanowires for dual-amplified fluorescence anisotropy assay of small molecules
  • 151.  High-sensitivity naphthalene-based two-photon fluorescent probe suitable for direct bioimaging of H2S in living cells

    Mao, GJ; Wei, TT ; Wang, XX ; Huan, SY ; Lu, DQ ; Zhang, J ; Zhang, XB ; Tan, WH ; Shen, GL ; Yu, RQ

    Analytical Chemistry, 7875-7881.DOI: 10.1021/ac401518e,[2013]>> Fulltext Link

    High-sensitivity naphthalene-based two-photon fluorescent probe suitable for direct bioimaging of H2S in living cells
  • 152.  Versatile DNAzyme-based amplified biosensing platforms for nucleic acid, protein, and enzyme activity detection

    Zhao, XH ; Gong, L ; Zhang, XB ; Yang, B; Fu, T; Hu, R ; Tan, WH ; Yu, RQ

    Analytical Chemistry, 3614-3620.DOI: 10.1021/ac303457u,[2013]>> Fulltext Link

    Versatile DNAzyme-based amplified biosensing platforms for nucleic acid, protein, and enzyme activity detection
  • 153.  A superquenched DNAzyme-perylene complex: a convenient, universal and low-background strategy for fluorescence catalytic biosensors

    Fu, T ; Zhao, XH ; Bai, HR ; Zhao, ZL ; Hu, R ; Kong, RM ; Zhang, XB ; Tan, WH ; Yu, RQ

    Chemical Communications, 6644-6646.DOI: 10.1039/c3cc43054e,[2013]>> Fulltext Link

    A superquenched DNAzyme-perylene complex: a convenient, universal and low-background strategy for fluorescence catalytic biosensors
  • 154.  Magnetic graphitic nanocapsules for programmed DNA fishing and detection

    Song, ZL ; Zhao, XH ; Liu, WN ; Ding, D ; Bian, X; Liang, H ; Zhang, XB ; Chen, Z; Tan, WH

    Small, 951-957.DOI: 10.1002/smll.201201975,[2013]>> Fulltext Link

    Magnetic graphitic nanocapsules for programmed DNA fishing and detection
  • 155.  Fluorosurfactant-capped gold nanoparticles-based label-free colorimetric assay for Au3+ with tunable dynamic range via a redox strategy

    Yang, B ; Zhang, XB ; Liu, WN ; Hu, R; Tan, WH ; Shen, GL ; Yu, RQ

    Biosensors and Bioelectronics, 1-5.DOI: 10.1016/j.bios.2013.03.044,[2013]>> Fulltext Link

    Fluorosurfactant-capped gold nanoparticles-based label-free colorimetric assay for Au3+ with tunable dynamic range via a redox strategy
  • 156.  Double-strand DNA-templated formation of copper nanoparticles as fluorescent probe for label free nuclease enzyme detection

    Hu, R; Liu, YR ; Kong, RM ; Donovan, MJ ; Zhang, XB ; Tan, WH; Shen, GL ; Yu, RQ

    Biosensors and Bioelectronics, 31-35.DOI: 10.1016/j.bios.2012.10.037,[2013]>> Fulltext Link

    Double-strand DNA-templated formation of copper nanoparticles as fluorescent probe for label free nuclease enzyme detection
  • 157.  An efficient fluorescent sensing platform for biomolecules based on fenton reaction triggered molecular beacon cleavage strategy

    Hu, R ; Liu, YR ; Zhang, XB ; Tan, WH ; Shen, GL ; Yu, RQ

    Biosensors and Bioelectronics, 442-445.DOI: 10.1016/j.bios.2012.09.013,[2013]>> Fulltext Link

    An efficient fluorescent sensing platform for biomolecules based on fenton reaction triggered molecular beacon cleavage strategy
  • 158.  Label-free dsDNA-Cu NPs-based fluorescent probe for highly sensitive detection of L-histidine

    Liu, YR ; Hu, R ; Liu, T ; Zhang, XB ; Tan, WH ; Shen, GL ; Yu, RQ

    Talanta, 402-407.DOI: 10.1016/j.talanta.2013.01.038,[2013]>> Fulltext Link

    Label-free dsDNA-Cu NPs-based fluorescent probe for highly sensitive detection of L-histidine
  • 159.  核酸适体及其衍生物的用途

    谭蔚泓、上官棣华

    发明专利, ZL 2009100830800,[2013]>> Fulltext Link

  • 160.  一种检测组氨酸标签重组蛋白的核酸适配体分子信标探针及其检测方法

    谭蔚泓、张晓兵、谭晓红、丁玎

    发明专利, ZL 201210193143X,[2013]>> Fulltext Link

  • 161.  一种用于靶向治疗的核酸载药系统及其制备方法

    谭蔚泓、朱贵志

    发明专利, ZL 2012101931444,[2013]>> Fulltext Link

  • 162.  A logical molecular circuit for programmable and autonomous regulation of protein activity using DNA aptamer-protein interactions

    Han, D ; Zhu, Z ; Wu, CC ; Peng, L ; Zhou, LJ ; Gulbakan, B ; Zhu, GZ ; Williams, KR ; Tan, WH

    Journal of the American Chemical Society, 20797-20804. DOI: 10.1021/ja310428s,[2012]>> Fulltext Link

    A logical molecular circuit for programmable and autonomous regulation of protein activity using DNA aptamer-protein interactions
  • 163.  Fabricating a reversible and regenerable Raman-active substrate with a biomolecule-controlled DNA nanomachine

    Zheng, J ; Jiao, AL ; Yang, RH ; Li, HM ; Li, JS ; Shi, ML ; Ma, C; Jiang, Y ; Deng, L; Tan, WH

    Journal of the American Chemical Society, 19957-19960.DOI: 10.1021/ja308875r,[2012]>> Fulltext Link

    Fabricating a reversible and regenerable Raman-active substrate with a biomolecule-controlled DNA nanomachine
  • 164.  Photon-manipulated drug release from a mesoporous nanocontainer controlled by azobenzene-modified nucleic acid

    Yuan, Q; Zhang, YF ; Chen, T; Lu, DQ ; Zhao, ZL ; Zhang, XB ; Li, ZX; Yan, CH ; Tan, WH

    ACS Nano, 6337-6344.DOI: 10.1021/nn3018365,[2012]>> Fulltext Link

    Photon-manipulated drug release from a mesoporous nanocontainer controlled by azobenzene-modified nucleic acid
  • 165.  Semiquantification of ATP in live cells using nonspecific desorption of DNA from graphene oxide as the internal reference

    Tan, XH ; Chen, T; Xiong, XL ; Mao, Y ; Zhu, GZ; Yasun, E ; Li, CM ; Zhu, Z ; Tan, WH

    Analytical Chemistry, 8622-8627.DOI: 10.1021/ac301657f,[2012]>> Fulltext Link

    Semiquantification of ATP in live cells using nonspecific desorption of DNA from graphene oxide as the internal reference
  • 166.  Molecular beacon aptamers for direct and universal quantitation of recombinant proteins from cell lysates

    Tan, XH ; Chen, WJ ; Lu, S ; Zhu, Z; Chen, T ; Zhu, GZ ; You, MX ; Tan, WH

    Analytical Chemistry, 8272-8276.DOI: 10.1021/ac301764q,[2012]>> Fulltext Link

    Molecular beacon aptamers for direct and universal quantitation of recombinant proteins from cell lysates
  • 167.  Endonucleolytic inhibition assay of DNA/Fok I transducer as a sensitive platform for homogeneous fluorescence detection of small molecule-protein interactions

    Zhen, Z ; Tang, LJ ; Lin, J ; Jiang, JH ; Yu, RQ ; Xiong, XL ; Tan, WH

    Analytical Chemistry, 5708-5715.DOI: 10.1021/ac300889t,[2012]>> Fulltext Link

    Endonucleolytic inhibition assay of DNA/Fok I transducer as a sensitive platform for homogeneous fluorescence detection of small molecule-protein interactions
  • 168.  Bifunctional fluoroionphore-ionic liquid hybrid for toxic heavy metal ions: improving its performance via the synergistic extraction strategy

    Jin, Z ; Xie, DX; Zhang, XB ; Gong, YJ ; Tan, WH

    Analytical Chemistry, 4253-4257.DOI: 10.1021/ac300676v,[2012]>> Fulltext Link

    Bifunctional fluoroionphore-ionic liquid hybrid for toxic heavy metal ions: improving its performance via the synergistic extraction strategy
  • 169.  Efficient fluorescence turn-on probe for zirconium via a target-triggered DNA molecular beacon strategy

    Meng, HM ; Fu, T ; Zhang, XB ; Wang, NN ; Tan, WH ; Shen, GL; Yu, RQ

    Analytical Chemistry, 2124-2128.DOI: 10.1021/ac300005f,[2012]>> Fulltext Link

    Efficient fluorescence turn-on probe for zirconium via a target-triggered DNA molecular beacon strategy
  • 170.  Through bond energy transfer: a convenient and universal strategy toward efficient ratiometric fluorescent probe for bioimaging applications

    Gong, YJ ; Zhang, XB ; Zhang, CC ; Luo, AL ; Fu, T ; Tan, WH ; Shen, GL; Yu, RQ

    Analytical Chemistry, 10777-10784.DOI: 10.1021/ac302762d,[2012]>> Fulltext Link

    Through bond energy transfer: a convenient and universal strategy toward efficient ratiometric fluorescent probe for bioimaging applications
  • 171.  Nucleic acid aptamers: an emerging frontier in cancer therapy

    Zhu, GZ ; Ye, M ; Donovan, MJ ; Song, EQ ; Zhao, ZL ; Tan, WH

    Chemical Communications, 10472-10480.DOI: 10.1039/c2cc35042d,[2012]>> Fulltext Link

    Nucleic acid aptamers: an emerging frontier in cancer therapy
  • 172.  A proximity-dependent surface hybridization strategy for constructing an efficient signal-on electrochemical DNAzyme sensing system

    Hu, R ; Fu, T ; Zhang, XB; Kong, RM ; Qiu, LP ; Liu, YR ; Liang, XT ; Tan, WH ; Shen, GL ; Yu, RQ

    Chemical Communications, 9507-9509.DOI: 10.1039/c2cc34848a,[2012]>> Fulltext Link

    A proximity-dependent surface hybridization strategy for constructing an efficient signal-on electrochemical DNAzyme sensing system
  • 173.  Generating aptamers by Cell-Selex for applications in molecular medicine

    Ye, M ; Hu, J ; Peng, MY ; Liu, J ; Liu, J ; Liu, HX ; Zhao, XL ; Tan, WH

    International Journal of Molecular Sciences , 3341-3353.DOI: 10.3390/ijms13033341,[2012]>> Fulltext Link

    Generating aptamers by Cell-Selex for applications in molecular medicine
  • 174.  Pyrene-excimer probes based on the hybridization chain reaction for the detection of nucleic acids in complex biological fluids

    Huang, J ; Wu, YR ; Chen, Y ; Zhu, Z ; Yang, XH ; Yang, CJ ; Wang, KM ; Tan, WH

    Angewandte Chemie International Edition, 401-404. DOI: 10.1002/anie.201005375,[2011]>> Fulltext Link

    Pyrene-excimer probes based on the hybridization chain reaction for the detection of nucleic acids in complex biological fluids
  • 175.  A ligation-triggered DNAzyme cascade for amplified fluorescence detection of biological small molecules with zero-background signal

    Lu, LM ; Zhang, XB ; Kong, RM ; Yang, B ; Tan, WH

    Journal of the American Chemical Society, 11686-11691. DOI: 10.1021/ja203693b,[2011]>> Fulltext Link

    A ligation-triggered DNAzyme cascade for amplified fluorescence detection of biological small molecules with zero-background signal
  • 176.  A nanoscale DNA-Au dendrimer as a signal amplifier for the universal design of functional DNA-based SERS biosensors

    Sun, YH ; Kong,RM ; Lu, DQ ; Zhang, XB ; Meng, HM; Tan, WH ; Shen, GL ; Yu, RQ

    Chemical Communications, 3840-3842.DOI: 10.1039/c0cc05133k,[2011]>> Fulltext Link

    A nanoscale DNA-Au dendrimer as a signal amplifier for the universal design of functional DNA-based SERS biosensors
  • 177.  Nucleic acid-functionalized nanomaterials for bioimaging applications

    Hu, R ; Zhang, XB ; Kong, RM ; Zhao, XH ; Jiang, JH ; Tan, WH

    Analytical Chemistry, 16323-16334.DOI: 10.1039/c1jm12588e,[2011]>> Fulltext Link

    Nucleic acid-functionalized nanomaterials for bioimaging applications
  • 178.  Molecular beacon-based junction probes for efficient detection of nucleic acids via a true target-triggered enzymatic recycling amplification

    Kong, RM ; Zhang, XB ; Zhang, LL ; Huang, Y ; Lu, DQ ; Tan, WH ; Shen, GL ; Yu, RQ

    Analytical Chemistry, 14-17.DOI: 10.1021/ac1025072,[2011]>> Fulltext Link

    Molecular beacon-based junction probes for efficient detection of nucleic acids via a true target-triggered enzymatic recycling amplification
  • 179.  Unimolecular catalytic DNA biosensor for amplified detection of L-histidine via an enzymatic recycling cleavage strategy

    Kong, RM ; Zhang, XB; Chen, Z ; Meng, HM ; Song, ZL ; Tan, WH ; Shen, GL ; Yu, RQ

    Analytical Chemistry, 7603-7607.DOI: 10.1021/ac2018926,[2011]>> Fulltext Link

    Unimolecular catalytic DNA biosensor for amplified detection of L-histidine via an enzymatic recycling cleavage strategy
  • 180.  Graphene-DNAzyme based biosensor for amplified fluorescence "turn-on" detection of Pb2+ with a high selectivity

    Zhao, XH ; Kong, RM ; Zhang, XB ; Meng, HM ; Liu, WN ; Tan, WH ; Shen, GL ; Yu, RQ

    Analytical Chemistry, 5062-5066.DOI: 10.1021/ac200843x,[2011]>> Fulltext Link

    Graphene-DNAzyme based biosensor for amplified fluorescence "turn-on" detection of Pb2+ with a high selectivity
  • 181.  Aptamer-conjugated nanomaterials and their applications

    Yang, L ; Zhang, XB ; Ye, M ; Jiang, JH; Yang, RH; Fu, T; Chen, Y ; Wang, KM; Liu, C; Tan, WH

    Advanced Drug Delivery Reviews, 1361-1370. DOI: 10.1016/j.addr.2011.10.002,[2011]>> Fulltext Link

    Aptamer-conjugated nanomaterials and their applications
  • 182.  Amplified detection of cocaine based on strand-displacement polymerization and fluorescence resonance energy transfer

    Huang, J ; Chen, Y ; Yang, L ; Zhu, Z ; Zhu, GZ ; Yang, XH; Wang, KM ; Tan, WH

    Biosensors and Bioelectronics, 450-453.DOI: 10.1016/j.bios.2011.05.038,[2011]>> Fulltext Link

    Amplified detection of cocaine based on strand-displacement polymerization and fluorescence resonance energy transfer
  • 183.  Aptamer-assembled nanomaterials for biosensing and biomedical applications

    Kong, RM ; Zhang, XB ; Chen, Z ; Tan, WH

    Small, 2428-2436.DOI: 10.1002/smll.201100250,[2011]>> Fulltext Link

    Aptamer-assembled nanomaterials for biosensing and biomedical applications
  • 184.  Single-walled carbon nanotubes as optical materials for biosensing

    Chen, Z ; Zhang, XB ; Yang, RH ; Zhu, Z ; Chen, Y ; Tan, WH

    Nanoscale, 1949-1956.DOI: 10.1039/c0nr01014f,[2011]>> Fulltext Link

    Single-walled carbon nanotubes as optical materials for biosensing
  • 185.  Molecular aptamers for drug delivery

    Tan, WH ; Wang, H ; Chen, Y ; Zhang, XB ; Zhu, HZ ; Yang, CY ; Yang, RH ; Liu, C

    Trends Biotechnology, 634-640.DOI: 10.1016/j.tibtech.2011.06.009,[2011]>> Fulltext Link

    Molecular aptamers for drug delivery
  • 186.  基于cell-SELEX的核酸适配体-纳米材料复合物用于癌细胞检测研究进展

    孔荣梅,陈卓,叶茂,张晓兵*,谭蔚泓*

    Science China-Chemistry, 1659.,[2011]>> Fulltext Link

    基于cell-SELEX的核酸适配体-纳米材料复合物用于癌细胞检测研究进展
  • 187.  Competition-mediated pyrene-switching aptasensor: probing lysozyme in human serum with a monomer-excimer fluorescence switch

    Huang, J ; Zhu, Z ; Bamrungsap, S ; Zhu, GZ ; You, MX ; He, XX ; Wang, KM ; Tan, WH

    Analytical Chemistry, 10158-10163. DOI: 10.1021/ac102277p,[2010]>> Fulltext Link

    Competition-mediated pyrene-switching aptasensor: probing lysozyme in human serum with a monomer-excimer fluorescence switch
  • 188.  In vivo fluorescence imaging of tumors using molecular aptamers generated by Cell-SELEX

    Shi, H ; Tang, ZW ; Kim, Y ; Nie, HL ; Huang, YF ; He, XX ; Deng, K ; Wang, KM ; Tan, WH

    Chemistry-An Asian Journal, 2209-2213. DOI: 10.1002/asia.201000242,[2010]>> Fulltext Link

    In vivo fluorescence imaging of tumors using molecular aptamers generated by Cell-SELEX